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Related Experiment Videos

Costs for heart failure with normal vs reduced ejection fraction.

Lawrence Liao1, James G Jollis, Kevin J Anstrom

  • 1Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA. liao0002@mc.duke.edu

Archives of Internal Medicine
|January 13, 2006
PubMed
Summary

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Heart failure with normal ejection fraction (HFNEF) in the elderly incurs costs similar to heart failure with reduced ejection fraction (HFrEF). This highlights the significant financial burden of HFNEF in older adults.

Area of Science:

  • Cardiology
  • Health Economics

Background:

  • Heart failure with normal ejection fraction (HFNEF) is increasingly prevalent in the elderly population.
  • Limited data exist on the economic impact and healthcare resource utilization of HFNEF compared to heart failure with reduced ejection fraction (HFrEF).

Purpose of the Study:

  • To compare the healthcare costs and resource utilization between elderly patients with HFNEF and HFrEF.
  • To assess the 5-year financial burden associated with HFNEF in a population-based cohort.

Main Methods:

  • A prospective, population-based cohort study of 4549 participants from the National Heart, Lung, and Blood Institute Cardiovascular Health Study.
  • 881 participants with heart failure were categorized into normal or abnormal ejection fraction (EF) groups using echocardiography or clinical assessments.

Related Experiment Videos

  • Medicare claims data from 1992-1998 were linked to calculate 5-year mean costs per subject using semiparametric estimators.

    • Main Results:

    • The study identified 495 participants with HFNEF and 386 with abnormal EF.
    • Participants with abnormal EF had higher rates of cardiology encounters and cardiac procedures.
    • Despite differences in procedures, 5-year costs were similar between HFNEF and HFrEF groups, both for prevalent ($32,580 vs $33,023) and incident ($45,604 vs $49,128) cases, even after accounting for comorbidities.

    Conclusions:

    • Elderly patients with HFNEF consume healthcare resources comparable to those with HFrEF over a 5-year period.
    • These findings underscore the significant and often underestimated financial burden of HFNEF in the elderly population.
    • Further research into cost-effective management strategies for HFNEF is warranted.