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Updated: Aug 13, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
Autologous peripheral blood stem cell transplantation for POEMS syndrome
S Kuwabara1, S Misawa, K Kanai
1Department of Neurology, Chiba University School of Medicine, Japan. kuwabara-s@faculty.chiba-u.jp
Abstract:
Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome is a rare multisystem disorder. Overproduction of vascular endothelial growth factor (VEGF) by plasmocytoma could be responsible for the symptoms. The authors treated four patients with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Within 6 months, symptoms associated with rapid normalization of serum VEGF levels improved.
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