Related Experiment Video
Updated: Aug 13, 2026

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
Published on: July 9, 2020
The oxygen and volatile anaesthetic delivery characteristics during spontaneous ventilation using a non-rebreathing
1Launceston Genereal Hospital, Launceston, Tasmania, Australia. studay@bigpond.com
Abstract:
The gas delivery characteristics during simulated spontaneous ventilation of a non-rebreathing adaptation of the Bain circuit were examined. Tidal volumes were varied from 200 to 600 ml and respiratory rate from 8 to 20 breaths per minute obtaining characteristics for a minute volume range from 2.4 to 12 litres/minute. The minimum inspired oxygen concentration with 1 litre/minute 100% oxygen fresh gas flow varied between 86 and 43% over the range of minute volumes. . The minimum inspired Sevoflurane concentration with a 4% vaporiser setting and a 1 litre/minute fresh gas flow varied between 3.4 and 1.3% over the range of minute volumes. Increasing minute volume was the primary determinant of decreasing minimum inspired concentrations with increasing respiratory rate having an independent but smaller effect in reducing concentrations. Thus this system was shown to be safe and economical for the use in spontaneous ventilation.
Related Concept Videos
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Oxygen Delivering System I: Nasal Cannula and Face Mask
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Inhalational Anesthetics: Overview
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
