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Stereotactic linac radiosurgery for arteriovenous malformations
B G Kenny1, E R Hitchcock, G Kitchen
1University of Birmingham, Midland Centre for Neurosurgery and Neurology, UK.
Journal of Neurology, Neurosurgery, and Psychiatry
|July 1, 1992
Summary
Stereotactic radiosurgery using a linear accelerator (linac) shows promising results for treating cerebral arteriovenous malformations. Early outcomes suggest a high obliteration rate and a success rate comparable to published data.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Neurology
Background:
- Stereotactic linear accelerator (linac) radiosurgery has been available in the West Midlands since 1987.
- It was the first such treatment facility in the United Kingdom.
Purpose of the Study:
- To evaluate the effectiveness and safety of linac radiosurgery for high-flow cerebral arteriovenous malformations.
- To assess treatment outcomes including lesion obliteration, size reduction, and complications.
Main Methods:
- Treatment of 42 patients with high-flow cerebral arteriovenous malformations using stereotactic linac radiosurgery.
- Follow-up included clinical assessment and angiography at one and 24 months post-treatment.
Main Results:
- Angiography at one year showed 5/26 lesions obliterated, 11/26 reduced in size/flow, and 10/26 unchanged.
- At 24 months, 9/10 reviewed patients achieved total obliteration.
- Complications occurred in three patients; two experienced hemorrhage, one unrelated death.
Conclusions:
- Linac radiosurgery demonstrates a high success rate for cerebral arteriovenous malformations, with significant obliteration achieved by 24 months.
- Early results are comparable to other published data, indicating its efficacy.
- While complications are noted, overall outcomes suggest a favorable risk-benefit profile for selected patients.
