Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatitis D.

P Husa1, A Linhartová, V Nemecek

  • 1Department of Infectious Diseases, University Hospital Brno, Jihlavska 20, 625 00 Brno, Czech Republic. phusa@med.muni.cz

Acta Virologica
|January 13, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adipokine Levels of RBP4, Resistin and Nesfatin-1 in Women Diagnosed With Gestational Diabetes.

Physiological research·2025
Same author

Extracellular vesicles in infectious diseases - importance and perspectives.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne·2023
Same author

Decreasing neutralization antibody levels following vaccination against SARS-CoV-2 in the elderly: an observational study in Southern Moravia, Czech Republic.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne·2022
Same author

Increasing procoagulant activity of circulating microparticles in patients living with HIV.

Medecine et maladies infectieuses·2019
Same author

Progressive multifocal leukoencephalopathy - epidemiology, immune response, clinical differences, treatment.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne·2019
Same author

Fecal bacteriotherapy in the treatment of Clostridium difficile infection.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne·2019
Same journal

A novel deltacryptic virus identified in Allium cepa from Brazil.

Acta virologica·2023
Same journal

Kinetics of interferon-λ and receptor expression in response to in vitro respiratory viral infection.

Acta virologica·2023
Same journal

High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

Acta virologica·2023
Same journal

Attenuation of equine herpesvirus 1 through deletion of gE gene and its pathological evaluation in murine model.

Acta virologica·2023
Same journal

Instrument-free, visual and direct detection of porcine reproductive and respiratory syndrome viruses in resource-limited settings.

Acta virologica·2023
Same journal

Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches.

Acta virologica·2023
See all related articles

Hepatitis D virus (HDV), dependent on Hepatitis B virus (HBV), is rare in the Czech Republic. Current antiviral treatments, including high-dose alpha-interferon (alpha-IFN), show unsatisfactory results for hepatitis D patients.

Area of Science:

  • Hepatology
  • Virology
  • Infectious Diseases

Background:

  • Hepatitis D virus (HDV) is an RNA virus requiring Hepatitis B virus (HBV) for replication and pathogenicity.
  • HDV infection prevalence is notably low in the Czech Republic.
  • Existing therapeutic strategies for hepatitis D demonstrate limited efficacy.

Purpose of the Study:

  • To summarize the current understanding of Hepatitis D virus (HDV) infection.
  • To review the treatment outcomes for patients with hepatitis D in the Czech Republic.
  • To discuss the recommended therapeutic approach for hepatitis D.

Main Methods:

  • Literature review on HDV and HBV epidemiology.
  • Analysis of antiviral therapy outcomes for hepatitis D.

Related Experiment Videos

  • Examination of standard treatment protocols for hepatitis D.

    • Main Results:

    • HDV is an uncommon infection in the Czech Republic.
    • Antiviral therapy for hepatitis D yields unsatisfactory results.
    • High-dose alpha-interferon (alpha-IFN) is the generally recommended treatment.

    Conclusions:

    • Hepatitis D represents a significant clinical challenge due to its dependence on HBV and limited treatment options.
    • The ineffectiveness of current therapies underscores the need for novel treatment strategies.
    • Standard treatment involves high-dose alpha-interferon (alpha-IFN) for 12 months.