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Updated: Aug 13, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Generalized granuloma annulare
1Department of Dermatology, New York University School of Medicine, USA.
Abstract:
A 94-year-old man presented with a relatively asymptomatic eruption of his forearms, abdomen, and back comprising symmetric erythematous papules and plaques. Generalized granuloma annulare is an idiopathic disorder that occurs more commonly in older patients and is characterized by numerous flesh-colored-to-erythematous papules. It is distinguished histologically by palisading granulomas with central connective tissue degeneration and with central mucin. Therapy has been attempted with various modalities with moderate efficacy.
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