Related Experiment Video
Updated: Aug 13, 2026

Super-Resolution Imaging of Bacterial Secreted Proteins Using Genetic Code Expansion
Published on: February 10, 2023
Gene-for-gene-mediated recognition of nuclear-targeted AvrBs3-like bacterial effector proteins
Sebastian Schornack1, Annett Meyer, Patrick Römer
1Institut für Genetik, Martin-Luther-Universität Halle-Wittenberg, 06099 Halle (Saale), Germany.
Abstract:
Plant disease resistance (R) genes mediate specific recognition of pathogens via perception of cognate avirulence (avr) gene products. The numerous highly similar AvrBs3-like proteins from the bacterial genus Xanthomonas provide together with their corresponding R proteins a unique biological resource to dissect the molecular basis of recognition specificity. A central question in this context is if R proteins that mediate recognition of structurally similar Avr proteins are themselves functionally similar or rather dissimilar. The recent isolation of rice xa5, rice Xa27 and tomato Bs4, R genes that collectively mediate recognition of avrBs3-like genes, provides a first clue to the molecular mechanisms that plants employ to detect AvrBs3-like proteins. Their initial characterization suggests that these R proteins are structurally and functionally surprisingly diverge. This review summarizes the current knowledge on R-protein-mediated recognition of AvrBs3-like proteins and provides working models on how recognition is achieved at the molecular level.
Related Concept Videos
Regulation of Bacterial Virulence
Regulation of Nuclear Protein Sorting
CRISPR and crRNAs
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
Reporter Genes
Commonly used reporter...
Leaky Scanning
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...

