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International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with
Deepak L Bhatt1, P Gabriel Steg, E Magnus Ohman
1Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. bhattd@ccf.org
JAMA
|January 13, 2006
Summary
Atherothrombosis risk factors like hypertension and diabetes are common globally but undertreated. This international study highlights the need for better management of these cardiovascular disease risks worldwide.
Area of Science:
- Cardiovascular Medicine
- Epidemiology
- Public Health
Background:
- Atherothrombosis is a major global cause of cardiovascular morbidity and mortality.
- International data on atherosclerosis risk factors and treatment intensity are lacking.
Purpose of the Study:
- To assess the global prevalence of atherosclerosis risk factors and treatment patterns.
- To determine if these patterns are comparable across different countries.
Main Methods:
- The Reduction of Atherothrombosis for Continued Health (REACH) Registry collected data from 67,888 patients in 44 countries (2003-2004).
- Included patients had established arterial disease or multiple risk factors.
- Assessed baseline prevalence of risk factors, medication use, and risk factor control.
Main Results:
- Consistent global risk factor profiles: high rates of hypertension (81.8%), hypercholesterolemia (72.4%), and diabetes (44.3%).
- Obesity rates were highest in North America.
- Patients were undertreated with statins, antiplatelet agents, and other therapies; hypertension and hyperglycemia were common.
Conclusions:
- Classic cardiovascular risk factors are prevalent and consistent worldwide.
- These risk factors are significantly undertreated and undercontrolled globally.
- The findings emphasize the need for improved global strategies for managing atherothrombosis risk factors.
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