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Choroidal detachment after topical prostaglandin analogs: case report
Kessara Pathanapitoon1, Paradee Kunavisarut
1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. kpathana@med.cmu.ac.th
Summary
Topical prostaglandin analogs can cause delayed choroidal detachment, especially in pseudophakic patients with chronic angle closure glaucoma. Discontinuation of these glaucoma medications typically resolves the detachment.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Pharmacology
Background:
- Topical prostaglandin analogs are widely used for chronic angle closure glaucoma management.
- Choroidal detachment is a potential, though uncommon, side effect of ocular medications.
Observation:
- Three case reports detail delayed choroidal detachment following prostaglandin analog use.
- Cases involved travoprost, bimatoprost, and latanoprost in pseudophakic eyes with glaucoma.
- Detachment occurred between one week and two years after initiating treatment.
Findings:
- All reported cases of choroidal detachment resolved after discontinuing the prostaglandin analog.
- Pseudophakic status appears to be a risk factor for developing this adverse effect.
- The latency period for detachment varied significantly among the cases.
Implications:
- Ophthalmologists should consider choroidal detachment in pseudophakic glaucoma patients using prostaglandin analogs.
- Cautious use and monitoring are advised for this patient population.
- Further research may elucidate the precise mechanism and risk factors for this complication.
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