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Updated: Aug 13, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Nasal obstruction and its impact on sleep-related breathing disorders
Ph Rombaux1, G Liistro, M Hamoir
1Department of Otorhinolaryngology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium. philippe.rombaux@orlo.ucl.ac.be
Abstract:
Upper airway patency is essential during sleep in order to avoid sleep-related breathing disorders (SRBD). Nasal obstruction may have a negative impact on sleep quality and must be considered to be a co-factor in the pathophysiology of SRBD. In this paper we will discuss the relation between nasal physiology at night and sleep quality and the possible mechanisms between nasal obstruction and obstructive sleep apnea-hypopnea syndrome (OSAS). We will review the effect of the relief of nasal obstruction (with nasal dilators, medication and/or surgery) on SRBD. Also an algorithm on the management of OSAS patients when nasal surgery is indicated will be proposed.
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