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Amiodarone-induced hyperthyroidism in a patient with functioning papillary carcinoma of the thyroid and extensive
Gavin C Mackie1, Barry L Shulkin
1University of Michigan Medical Center, Ann Arbor, USA.
Abstract:
Thyroid hormone producing thyroid carcinoma is an uncommon cause of thyrotoxicosis. A patient with extensive hepatic metastases from well-differentiated carcinoma is presented. Administration of amiodarone for atrial fibrillation led to the development of hyperthyroidism. Precipitation of thyrotoxicosis by iodine-containing compounds in patients with thyroid carcinoma is rare. The relatively high iodine load and the slow elimination of amiodarone complicate the clinical management of such patients.
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