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Updated: Aug 13, 2026
08:38
Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
Published on: November 8, 2015
A case of Darier's disease successfully treated with topical tacrolimus
P Rubegni1, S Poggiali, P Sbano
1Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Italy. rubegni@unisi.it
Abstract:
Tacrolimus is a macrolide that inhibits T-cell activation. The most extensive experience with topical tacrolimus has been in treating atopic dermatitis but it has been used in various skin diseases, including Hailey-Hailey disease, with encouraging results. We report a case of extensive Darier's disease successfully treated with topical tacrolimus, after suspension of oral isotretrinoin due to major depression.
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