Related Experiment Video

Updated: Aug 13, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

Ventrogluteal area--a suitable site for intramuscular vaccination of infants and toddlers

I F Cook1, J Murtagh

  • 1Discipline of General Practice, School of Medical Practice and Population Health, University of Newcastle, Callaghan, NSW 2308, Australia. drifcook@bigpond.com

Vaccine
|January 13, 2006
PubMed

Insights

Buttock vaccination, specifically the ventrogluteal area, offers a safe and effective alternative for infant and toddler immunizations. This site demonstrates similar effectiveness to other common vaccination sites with potentially lower side effects.

Area of Science:

  • Pediatric Vaccinology
  • Anatomical Studies

Background:

  • Buttock vaccination is often avoided due to safety concerns, stemming from historical use of neurotoxic agents, not vaccines.
  • The ventrogluteal area is anatomically suitable for safe intramuscular injections.

Purpose of the Study:

  • To establish the ventrogluteal area as a viable site for intramuscular vaccination in infants and toddlers.
  • To develop age-specific anatomical templates for accurate injection site identification.

Main Methods:

  • Measurements were taken from 642 children aged 2-18 months to create age-specific templates.
  • An ultrasonographic study of 57 children (2-18 months) compared ventrogluteal tissue composition with the anterolateral thigh site.

Main Results:

  • The ventrogluteal area was clearly defined by the developed templates, confirming its suitability for intramuscular injection.
  • Ultrasonographic analysis validated the tissue composition of the ventrogluteal site for vaccination.

Conclusions:

  • The ventrogluteal area is a safe and suitable site for intramuscular vaccination in infants and toddlers.
  • This study provides evidence to support the use of the ventrogluteal site, potentially improving vaccination strategies.

More Related Videos

Intravenous Injections in Neonatal Mice05:17

Intravenous Injections in Neonatal Mice

Published on: November 11, 2014

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...