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Ossifying fibroma in a miniature rex rabbit (Oryctolagus cuniculus)
K A Whitten1, M M Popielarczyk, D A Belote
1Department of Veterinary Pathology, Armed Forces Institute of Pathology, 14th Street, Alaska Avenue North West, Washington DC 20306-6000, USA. kim.whitten@us.army.mil
Veterinary Pathology
|January 13, 2006
Summary
This study reports the first case of ossifying fibroma in a rabbit, a benign tumor affecting the jaw. The findings detail the histopathological characteristics of this rare condition in a miniature Rex rabbit.
Area of Science:
- Veterinary Pathology
- Comparative Oncology
Background:
- Ossifying fibroma is a benign neoplasm typically affecting the mandible in humans and animals, often causing cosmetic issues and malocclusion.
- This tumor is rare in animals, with young horses being the most frequently affected species.
Observation:
- A solitary mass was identified in the right maxillary region of a 6-year-old miniature Rex rabbit, extending beneath the gingiva.
- The mass presented as a pale pink, firm, nodular incisional biopsy specimen, causing expansion of the hard palate and overgrown teeth.
Findings:
- Histopathological examination revealed a neoplasm composed of fibroblastic cells within abundant collagen.
- Neoplastic cells were observed with osteoblasts, forming mineralized bony matrix with sparse lacunae, consistent with ossifying fibroma.
- Minimal inflammation was noted in the specimen.
Implications:
- This case represents the first documented instance of ossifying fibroma in a rabbit.
- The findings contribute to the understanding of rare neoplasms in lagomorphs and may inform future diagnostic and treatment approaches.
