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Updated: Aug 13, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Clinical acute renal failure: diagnosis and management
Amit Mitra1, Einath Zolty, Wei Wang
1Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, 80262, USA.
Abstract:
Acute renal failure (ARF) is frequently encountered in the hospitalized setting. In this article, we discuss the etiology, pathogenesis, preventative therapies, and renal replacement strategies in patients with acute tubular necrosis, the most common form of hospitalized ARF.
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Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
