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[Diclofenac during prostate needle biopsy. Significant pain reduction]
1Abteilung für Urologie, Asklepios Klinik Barmbek, Hamburg. thorsten.bach@hansenet.de
Der Urologe. Ausg. A
|January 13, 2006
Summary
Diclofenac suppositories effectively reduced pain during prostate biopsies. Patients receiving diclofenac reported less pain and were more willing to undergo future biopsies compared to placebo or control groups.
Area of Science:
- Urology
- Pharmacology
- Pain Management
Context:
- Prostate biopsy is a common procedure for diagnosing prostate cancer.
- Pain and discomfort are frequently reported during and after prostate biopsies.
- Current pain management strategies may not be fully effective for all patients.
Purpose:
- To evaluate the efficacy of diclofenac suppositories in reducing pain associated with prostate biopsy.
- To compare pain scores and patient willingness for repeat procedures between diclofenac, placebo, and control groups.
Summary:
- A randomized study involving 228 patients undergoing prostate biopsy compared intrarectal lidocaine gel with additional placebo or 50 mg diclofenac suppositories.
- Patients in the diclofenac group reported significantly lower pain scores (Visual Analog Scale) post-biopsy.
- Fewer patients in the diclofenac group refused repeat biopsies compared to placebo and control groups (11% vs. 25-34%, p<0.05).
Impact:
- Pre-biopsy administration of diclofenac suppositories offers a simple and effective method for pain reduction in prostate biopsy patients.
- Improved pain management may enhance patient compliance and reduce anxiety associated with the procedure.
- Diclofenac represents a valuable addition to the analgesic armamentarium for urological procedures.