Related Experiment Video
Updated: Aug 13, 2026
Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
[Diclofenac during prostate needle biopsy. Significant pain reduction]
1Abteilung für Urologie, Asklepios Klinik Barmbek, Hamburg. thorsten.bach@hansenet.de
Background:
The aim of this study was to evaluate the efficacy of diclofenac to reduce pain during prostate biopsy.
Methods:
After prospective randomization all patients received an intrarectal lidocaine gel instillation. Group 1 (n=80) functioned as control group, group 2 (n=72) received a placebo, and group 3 (n=76) a 50 mg diclofenac suppository in addition. Patients were asked to identify their pain score (VAS 10) after the biopsy. Two weeks later, the patients were called and asked about the post-biopsy course.
Results:
Patients in the diclofenac group had significantly lower pain scores than control or placebo group patients. Another biopsy without additional anesthesia was refused by 25% of the control group and 34% of the placebo group, but only by 11% of the diclofenac group (p<0.05).
Conclusions:
The preinterventional administration of diclofenac suppositories is a simple but efficient procedure for pain reduction in patients who undergo prostate biopsy.
