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[Age and gender difference in rheumatology]
1Division of Medical Informatics, Chiba University Hospital.
Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
|January 18, 2006
Summary
Collagen diseases show varying gender prevalence, with aging impacting systemic lupus erythematosus incidence differences. Steroid treatment for conditions like rheumatoid arthritis can lead to diabetes mellitus and hyperlipidemia, especially in older adults.
Area of Science:
- Rheumatology and Endocrinology
- Geriatric Medicine
Context:
- Collagen diseases exhibit distinct gender prevalences, with exceptions like polyarteritis nodosa.
- Aging influences gender-based incidence disparities in certain autoimmune conditions, such as systemic lupus erythematosus.
- Steroid therapy introduces significant comorbidities, including diabetes mellitus and hyperlipidemia, particularly in elderly patients.
Purpose:
- To analyze the impact of aging on gender differences in collagen diseases.
- To identify common complications associated with steroid treatment in elderly patients with rheumatic diseases.
Summary:
- Gender prevalence in collagen diseases is not uniform; while many are more common in women, aging can reduce these differences.
- Systemic lupus erythematosus shows diminishing gender incidence gaps with age, whereas Sjögren syndrome remains more prevalent in women across all age groups.
- Diabetes mellitus and hyperlipidemia are frequent steroid-induced complications, with diabetes more prevalent over 45 and hyperlipidemia across all ages, peaking between 45-54.
Impact:
- Highlights the need for age- and gender-specific management strategies for collagen diseases.
- Emphasizes careful monitoring and management of steroid-related complications like diabetes and hyperlipidemia in elderly patients undergoing treatment for conditions such as rheumatoid arthritis.