[Effects of subchronic introduction of phenamine and haloperidol on development of spontaneous catalepsy in mice]

The development of spontaneous and haloperidol-provoked catalepsy was investigated in more than 200 mice. It was found that spontaneous and haloperidolic catalepsies have the same mechanism of development. Injections of amphetamine followed by injections of haloperidol led to persistent changes of cateleptogenic behavior in mice. Less duration of spontaneous catalepsy may reflect functional condition of catecholaminergic brain systems similar to that of patients with psychotic disorder.