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Updated: Aug 12, 2026

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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Fungal endogenous endophthalmitis--case report]
Benone Cârstocea1, Monica Armegioiu, Simona Buliga
1Spital Clinic de Urgenţă Militar Central, Bucureşti.
Summary
This case study details a late diagnosis of endogenous Candida endophthalmitis in a high-risk patient. Surgical intervention with posterior vitrectomy successfully treated the condition.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Mycology
Background:
- Endogenous fungal endophthalmitis is a rare but serious intraocular infection.
- Candida species are the most common cause of endogenous fungal endophthalmitis.
- Patients with risk factors such as diabetes, intravenous drug use, and immunosuppression are at higher risk.
Observation:
- A patient with multiple risk factors presented with symptoms suggestive of endophthalmitis.
- Diagnosis was delayed, complicating the management of the infection.
- The patient developed endogenous Candida endophthalmitis, a severe intraocular inflammation.
Findings:
- The causative organism was identified as Candida species.
- Despite the delayed diagnosis, the patient's vision was ultimately preserved.
- Posterior vitrectomy was performed as the surgical solution.
Implications:
- This case highlights the importance of early diagnosis and prompt treatment of endogenous fungal endophthalmitis.
- Aggressive management, including surgical intervention, can lead to favorable outcomes even in complex cases.
- Identifying and managing risk factors is crucial for preventing this sight-threatening condition.
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