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Updated: Aug 13, 2026

Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry
Published on: March 24, 2023
Facile peripheral modification of N-confused porphyrin
Wenchao Qu1, Tang Ding, Anil Cetin
1Department of Chemistry, Knight Chemical Laboratory, University of Akron, Akron, Ohio 44325-3601, USA.
Abstract:
[reaction: see text] An improved methodology for the N-alkylation of the porphyrin isomer N-confused porphyrin is presented. The combination of polar solvent conditions and the use of the base Cs2CO3 affords externally modified products in high yield without separation difficulties and without the use of large excesses of alkylating reagent. The further transformation and metalation of these products provides opportunities for the construction of metalloenzyme model complexes, peptide adducts, and chromophore assemblies.
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