Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antithrombotic therapy for congestive heart failure.

I Chung1, G Y H Lip

  • 1Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK.

International Journal of Clinical Practice
|January 18, 2006
PubMed
Summary

Congestive heart failure patients face higher risks of blood clots. This review examines stroke risks and antithrombotic therapy effectiveness and safety in heart failure patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Social determinants of health and clinical outcomes among patients with atrial fibrillation: evidence from a global federated health research network.

QJM : monthly journal of the Association of Physicians·2023
Same author

Pharmacokinetics and pharmacodynamics of direct oral anticoagulants.

Expert opinion on drug metabolism & toxicology·2023
Same author

Cerebrovascular risk factors and their time-dependent effects on stroke survival in the EMMA cohort study.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2023
Same author

Clinical phenotype classification to predict risk and optimize the management of patients with atrial fibrillation using the Atrial Fibrillation Better Care (ABC) pathway: a report from the COOL-AF registry.

QJM : monthly journal of the Association of Physicians·2023
Same author

Effectiveness of out-patient based acute heart failure care: a pilot randomised controlled trial.

Acta cardiologica·2023
Same author

Patient and Public Involvement and Engagement (PPIE): first steps in the process of the engagement in research projects in Brazil.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2022

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Pharmacology

Background:

  • Patients with congestive heart failure (CHF) exhibit an elevated risk of thromboembolic events.
  • Significant uncertainty exists regarding the optimal antithrombotic therapy for this patient population.
  • Limited evidence currently supports oral anticoagulation, with major trial data anticipated.

Purpose of the Study:

  • To review the current evidence on stroke and thromboembolic event risks in patients with CHF.
  • To evaluate the efficacy and safety of antithrombotic therapies in this cohort.
  • To address the ongoing debate surrounding antithrombotic treatment in heart failure.

Main Methods:

  • Systematic literature review of existing studies.
  • Analysis of randomized controlled trials and observational data.
  • Synthesis of evidence on antithrombotic drug risks and benefits.

Main Results:

  • Congestive heart failure patients have a demonstrably higher incidence of thromboembolic events.
  • Aspirin may pose risks in heart failure, potentially interacting with ACE inhibitors and increasing hospitalizations.
  • Evidence for oral anticoagulation is currently limited but expanding with new trial data.

Conclusions:

  • Further research and large-scale trials are crucial to guide antithrombotic therapy decisions in CHF.
  • The potential risks of aspirin in CHF warrant careful consideration.
  • A nuanced approach is needed to balance thromboembolic risk reduction with potential adverse effects of treatment.

Related Experiment Videos