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Tramadol for pain relief in children undergoing herniotomy: a comparison with ilioinguinal and iliohypogastric blocks
Mohammad Bagher Khosravi1, Sasan Khezri, Simin Azemati
1Department of Anesthesiology, Shiraz University of Medical Sciences, Shiraz, Iran. Khosravimb@sums.ac.ir
Insights
Intravenous tramadol provided effective pain relief for children after herniorrhaphy, comparable to ilioinguinal and iliohypogastric nerve blocks. While tramadol showed superior analgesia at peak times, it was associated with increased nausea and vomiting.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Pharmacology
Background:
- Postoperative pain control in children is a key anesthetic goal.
- Ilioinguinal and iliohypogastric nerve blocks are common for post-herniorrhaphy pain.
- Tramadol is an analgesic with mixed opioid and nonopioid properties.
Purpose of the Study:
- To compare the efficacy of intravenous tramadol versus ilioinguinal and iliohypogastric nerve blocks for managing post-herniorrhaphy pain in children aged 2-7 years.
Main Methods:
- Sixty pediatric patients undergoing herniorrhaphy were randomized into two groups.
- One group received intravenous tramadol (1.5 mg/kg) before anesthesia induction.
- The other group received ilioinguinal and iliohypogastric nerve blocks with bupivacaine (0.25 ml/kg) before skin incision.
Main Results:
- Both methods yielded similar pain scores at 1, 4, and 24 hours post-surgery.
- The tramadol group experienced significantly less pain at 2 and 3 hours post-surgery (P < 0.05).
- Nausea and vomiting were more frequent in the tramadol group (P < 0.05), with no respiratory depression in either group.
Conclusions:
- Intravenous tramadol offers comparable, and at times superior, analgesia to ilioinguinal and iliohypogastric nerve blocks for post-herniorrhaphy pain in children.
- The increased incidence of nausea and vomiting with tramadol warrants consideration regarding its overall benefit, despite its lack of respiratory depression.
Background:
Prevention of postoperative pain in children is one of the most important objectives of the anesthesiologist. Preoperative ilioinguinal and iliohypogastric nerve blocks have been widely used to provide analgesia in children undergoing herniorrhaphy. Tramadol is an analgesic with micro-opioid and nonopioid activity. In this study we compared the usage of intravenous tramadol with ilioinguinal and iliohypogastric nerve blocks for control of post-herniorrhaphy pain in children aged 2-7 years.
Methods:
Sixty patients were randomly allocated to two groups of thirty. One group received tramadol 1.5 mg.kg(-1) i.v. before induction of general anesthesia and the other had an ilioinguinal and iliohypogastric nerve block with 0.5% bupivacaine (0.25 ml.kg(-1)) before skin incision. We assessed pain using the Children's Hospital of Eastern Ontario Pain Scale and the Categorical Pain Scale.
Results:
At 1, 4 and 24 h after surgery the two groups had identical pain scores. At 2 and 3 h after surgery the tramadol group experienced significantly less pain (P < 0.05). The rescue drug for residual pain, was used equally in the two groups. None of the 60 patients had respiratory depression but the tramadol group patients were found to have more episodes of nausea and vomiting (P < 0.05).
Conclusions:
We concluded that tramadol can have at least the same analgesic effect as that of ilioinguinal and iliohypogastric nerve blocks for post-herniorrhaphy pain in children, with even a superior effect at the time of maximal analgesia. We also highlight the troublesome side-effect of nausea and vomiting which brings into question the benefits of using this opioid that seems to lack respiratory depression.
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