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Hereditary papulotranslucent acrokeratoderma: a case report and literature review
Julie K Sracic1, Ravi S Krishnan, Janna K Nunez-Gussman
1Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
Dermatology Online Journal
|January 18, 2006
Summary
Hereditary papulotranslucent acrokeratoderma is a rare genetic skin condition affecting hands and feet. This case report details a young woman
Area of Science:
- Dermatology
- Genetics
- Human Pathology
Background:
- Hereditary papulotranslucent acrokeratoderma is a rare autosomal-dominant disorder.
- It affects the hands and feet with characteristic skin changes.
- Associated features include fine scalp hair and atopic diathesis.
Observation:
- Presents a case of hereditary papulotranslucent acrokeratoderma in a young adult female.
- Describes the clinical presentation of asymptomatic, yellowish-white papules and plaques.
- Highlights histopathological findings of epidermal alterations.
Findings:
- Confirms focal hyperkeratosis, hypergranulosis, and acanthosis.
- Reviews existing literature on this rare genodermatosis.
- Discusses the differential diagnosis with acquired forms.
Implications:
- Contributes to understanding rare genetic skin disorders.
- Aids in the diagnosis and management of hereditary papulotranslucent acrokeratoderma.
- Provides insights into the relationship between hereditary and acquired conditions.
