Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Topiramate and scars.

Rakesh Bharti, Lovedhi Agarwal

    Dermatology Online Journal
    |January 18, 2006
    PubMed
    Summary

    Topiramate shows promise as a safe and effective scar treatment. Studies indicate good to excellent results for post-acne and post-varicella scars, suggesting potential for various scar types.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Rapid Progression of Linear Porokeratosis Following COVID-19 Vaccination: A Case Report.

    Indian dermatology online journal·2025
    Same author

    Microneedling with Dermaroller 192 needles along with 5-fluorouracil solution in the treatment of stable vitiligo.

    Journal of the American Academy of Dermatology·2019
    Same author

    Mucous membrane plasmacytosis: a case report and review of the literature.

    Dermatology online journal·2004
    See all related articles

    Area of Science:

    • Dermatology
    • Pharmacology

    Background:

    • Topiramate is an anticonvulsant medication.
    • Scarring can result from various dermatological conditions.
    • Existing treatments for scars have limitations.

    Purpose of the Study:

    • To evaluate the efficacy and safety of oral topiramate for treating diverse scar types.
    • To assess topiramate's effectiveness in improving scar appearance and texture.

    Main Methods:

    • An open-label study involving ten adult subjects with aged scars.
    • Subsequent treatment of 91 patients with conditions like acne, varicella, and keloids.
    • Oral topiramate dosage initiated at 15 mg/day, increased to 30 mg/day if needed.

    Main Results:

    • Excellent to good outcomes were observed in patients with post-acne scars.
    • Significant improvement was noted in post-varicella scars.
    • Topiramate demonstrated a favorable safety profile in the treated subjects.

    Conclusions:

    • Oral topiramate may be a safe and effective therapeutic option for managing certain types of scars.
    • Further research is warranted to confirm these findings across a broader patient population and scar types.

    Related Experiment Videos