Related Experiment Video

Updated: Aug 13, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
06:08

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

Published on: February 7, 2014

Carotid atherosclerosis and arterial peripheral pulse wave velocity in cerebral thrombosis

Tamaki Tomonori1, Sawada Keiko, Hayashi Shinkichi

  • 1Department of Neurosurgery, Nippon Medical School Tamanagayama Hospital, 1-7-1 Nagayama Tama-shi, Tokyo-to, Japan 206-8512. tamakito@nms.ac.jp

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|January 18, 2006
PubMed

Insights

Arterial stiffness, measured by pulse wave velocity, is linked to the presence of carotid plaque in stroke patients. However, it does not correlate with the plaque

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Vascular Biology

Background:

  • Arterial stiffening and thickening are key features of atherosclerosis.
  • Understanding the link between large artery stiffness and thickening is crucial for preventing cerebrovascular disease.
  • Limited research exists on the correlation between carotid artery wall thickening and arterial stiffness.

Purpose of the Study:

  • To investigate the relationship between arterial stiffness and carotid plaque in patients with cerebral thrombosis.
  • To assess if arterial stiffness correlates with the presence and severity of carotid atherosclerosis.

Main Methods:

  • Study included 109 patients (aged 40-80) with cerebral thrombosis.
  • Arterial stiffness was assessed using ankle-brachial pulse wave velocity.
  • Carotid plaque was detected via high-resolution real-time B-mode ultrasonography, with plaque severity scored.

Main Results:

  • High pulse wave velocity was significantly associated with the existence of carotid plaque (p<0.001).
  • Pulse wave velocity was not significantly associated with the severity of carotid plaque (p=0.14).
  • Multivariate logistic regression models confirmed these findings.

Conclusions:

  • Ankle-brachial pulse wave velocity is associated with the presence of carotid atherosclerosis in patients with cerebral thrombosis.
  • Arterial stiffness is not associated with the severity of carotid atherosclerosis in this patient group.
  • Findings suggest pulse wave velocity may serve as an indicator for carotid atherosclerosis presence.

More Related Videos

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome06:04

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness05:51

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

Published on: May 3, 2018

Related Concept Videos

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Pulse01:16

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...