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Factors affecting time to pregnancy.

A Axmon1, L Rylander, M Albin

  • 1Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, Institute of Laboratory Medicine, University Hospital, Lund, Sweden. anna.axmon@med.lu.se

Human Reproduction (Oxford, England)
|January 18, 2006
PubMed
Summary
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Female reproductive health is influenced by lifestyle and environmental factors. However, biological factors, such as age and cycle length, were stronger predictors of time to pregnancy (TTP) than lifestyle choices in this study.

Area of Science:

  • Reproductive Epidemiology
  • Human Reproduction

Background:

  • Female reproductive health can be influenced by lifestyle, occupational, and environmental factors.
  • Investigating the interplay of these factors is crucial for understanding reproductive outcomes.

Purpose of the Study:

  • To examine the separate and joint effects of various lifestyle, occupational, and environmental factors on time to pregnancy (TTP).
  • To identify key predictors influencing fecundability in women.

Main Methods:

  • Retrospective data collection using self-administered questionnaires from 1578 randomly selected Swedish women.
  • Logistic regression analysis of survival data to calculate fecundability odds ratios.
  • Multivariate models to determine the most impactful factors on TTP.

Related Experiment Videos

Main Results:

  • Several lifestyle factors were associated with TTP, but only oral contraceptive use, menstrual cycle length, age at conception, and parity remained significant in multivariate models, explaining 14% of TTP variance.
  • After excluding early conceptions, age at conception and menstrual cycle length were the primary predictors, explaining 8% of TTP variance.
  • Biological factors demonstrated a greater impact on TTP than lifestyle factors.

Conclusions:

  • The studied factors explained a limited portion of the variation in observed time to pregnancies.
  • Female biological factors appear to be more significant predictors of TTP than investigated lifestyle factors.
  • Further research is needed to elucidate the complex determinants of fecundability.