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Updated: Aug 13, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
Spontaneous regression of bone metastasis from renal cell carcinoma; a case report
Takahiro Nakajima1, Makoto Suzuki, Soichiro Ando
1Division of Thoracic Diseases, Chiba Cancer Center, Japan. nakajii@fc.med.miyazaki-u.ac.jp
Background:
Spontaneous regression of metastatic renal cell carcinoma is rarely observed.
Case Presentation:
Metastatic renal cell carcinoma was identified in a 70-year-old male using computed tomography-guided percutaneous needle biopsy. Two months after the diagnosis, a partial resection of the sternal bone was performed. Pathological examination revealed granulated tissue with bleeding and necrosis but no carcinogenic cells.
Conclusion:
We report a pathologically identified case in which a sternal bone metastasis that was noticed two years after radical nephrectomy regressed completely and spontaneously.
