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Updated: Aug 13, 2026

Determination of the Procoagulant Activity of Extracellular Vesicle (EV) Using EV-Activated Clotting Time (EV-ACT)
Published on: August 4, 2023
Coagulation disorders in uremia
Daniela Molino1, Domenico De Lucia, Natale Gaspare De Santo
1Department of Nephrology, the Laboratory of Hemostasis and Thrombosis, and the PhD Program in Nephrological Sciences, Second University of Naples, Naples, Italy.
Abstract:
In patients with end-stage renal disease on maintenance hemodialysis, coagulation abnormalities such as hypercoagulability and thrombosis are common. Thrombotic complications in uremic patients are frequent and include those occurring at the vascular access and in the coronary, cerebral, and retinal arteries. Data do not entirely clarify the mechanisms involved and further investigations are necessary. Here we show a summary of coagulation and fibrinolytic disorders in uremia and the novelties foreseen in molecular biology.
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