Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ethics in Research

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.

Bioequivalence studies: Biowaivers

Bioequivalence studies: Biowaivers

In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Phosphatase specificity influences phosphorylation timing of CDK substrates during the cell cycle.

Nature communications·2025

Same author

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase.

Nature·2025

Same author

Science, Education, Leadership, and Politics: An Interview with Bruce Alberts and Paul Nurse.

Annual review of cell and developmental biology·2025

Same author

The discovery of cyclin-dependent kinases.

Nature reviews. Molecular cell biology·2024

Same author

We can make the UK a science superpower - with a radical political manifesto.

Nature·2024

Same author

CDK activity at the centrosome regulates the cell cycle.

Cell reports·2024

Search research articles

Related Experiment Video

Updated: Jul 15, 2026

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 3. Aerobiology

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 3. Aerobiology

Published on: October 3, 2016

US biomedical research under siege.

¹Rockefeller University, New York, NY 10021, USA. nurse@rockefeller.edu

|January 18, 2006

Summary

Biomedical research funding in the US has stagnated, creating significant pressure. Radical solutions are urgently needed to address this critical challenge in the research enterprise.

Area of Science:

Biomedical research
Health sciences
Scientific funding

Background:

US biomedical research funding faces stagnation.
This stagnation exerts considerable pressure on the research enterprise.
The current situation necessitates innovative approaches.

Purpose of the Study:

To highlight the critical issue of stagnant biomedical research funding in the US.
To advocate for the consideration of radical solutions to this funding crisis.

Main Methods:

Analysis of the current state of biomedical research funding.
Discussion of the pressures faced by the research enterprise.
Exploration of potential radical solutions.

Main Results:

More Related Videos

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Published on: September 22, 2021

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

Related Experiment Videos

Last Updated: Jul 15, 2026

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 3. Aerobiology

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 3. Aerobiology

Published on: October 3, 2016

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Published on: September 22, 2021

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

Biomedical research funding in the US is not growing.
The research community is under significant financial strain.
Existing funding models may be insufficient.

Conclusions:

The stagnation of biomedical research funding requires immediate attention.
Radical solutions must be explored to ensure the future of biomedical research.
Proactive and innovative strategies are essential for scientific progress.