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[Effect of intraperitoneal administration of sandoglobulin on peritoneal fluid IgG level in patients treated by
Z Wańkowicz1, E Panasiuk-Jarzyło, B Pietrzak
1Klinicznego Oddziału Dializoterapii CSK WAM, Warszawa.
In 6 patients (PTS) treated with SPD for 369 patient weeks (ptw) we evaluated the influence of three intraperitoneal SI on the IgG concentration in the PE. The concentration of IgG was checked before, on 1-st, 3-rd day 2-nd and 3-rd week after SI. In the course of the following 229 ptw, we observed three episodes of peritonitis (PN) in two pts, while in the control period of 140 ptw no PN occurred. The concentrations in PE of opsonins (IgG, C3 complement, fibronectin) at the start of SPD shoved enormous individual differences and did not correlate with occurrence of PN in the follow-up. Intraperitoneal SI caused significant increase of IgG in PE, but only to the third day after infusion. Our preliminary results do not confirm the protective effect of intraperitoneal SI on occurrence of PN in SPD patients.
In 6 patients (PTS) treated with SPD for 369 patient weeks (ptw) we evaluated the influence of three intraperitoneal SI on the IgG concentration in the PE. The concentration of IgG was checked before, on 1-st, 3-rd day 2-nd and 3-rd week after SI. In the course of the following 229 ptw, we observed three episodes of peritonitis (PN) in two pts, while in the control period of 140 ptw no PN occurred. The concentrations in PE of opsonins (IgG, C3 complement, fibronectin) at the start of SPD shoved enormous individual differences and did not correlate with occurrence of PN in the follow-up. Intraperitoneal SI caused significant increase of IgG in PE, but only to the third day after infusion. Our preliminary results do not confirm the protective effect of intraperitoneal SI on occurrence of PN in SPD patients.