Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MRI of normal fetal brain development.

Daniela Prayer1, Gregor Kasprian, Elisabeth Krampl

  • 1Department of Radiodiagnostics, Medical University of Vienna, Vienna, Austria. Daniela.prayer@meduniwien.ac.at

European Journal of Radiology
|January 18, 2006
PubMed
Summary

Magnetic resonance imaging (MRI) tracks fetal brain maturation from 18 weeks gestation. Key signal changes reflect histological development, aiding interpretation of brain development in vivo.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

What you see is not always what you get-MRI-based ganglionic eminence volumetry challenges subjective assessment in CNS anomalies.

European radiology·2026
Same author

Prenatal alcohol exposure affects placental degradation-a retrospective fetal MRI study.

European radiology·2026
Same author

Phenotyping trisomies 13 and 18 and CHARGE syndrome in fetal MRI-a proposed phenome-based, morphological disease severity score, and network medicine analysis.

European radiology·2026
Same author

Analysis of fetal MRI data reveals no effect on liver maturation following prenatal alcohol exposure.

European radiology·2026
Same author

The superficial subplate as an in vivo imaging biomarker of normal cortical development in humans- a 3T MRI feasibility study.

AJNR. American journal of neuroradiology·2026
Same author

A computational model of radial scaffolds in the human fetal brain based on MRI.

Cerebral cortex (New York, N.Y. : 1991)·2025

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Developmental Biology

Background:

  • Fetal brain maturation involves complex histological and cellular changes.
  • In vivo magnetic resonance imaging (MRI) is crucial for studying this development.
  • Understanding signal changes requires knowledge of tissue composition and organization.

Purpose of the Study:

  • To review the in vivo MRI appearance of fetal brain maturation.
  • To correlate MRI findings with histological and anatomical data.
  • To detail the development of specific brain structures and transient features.

Main Methods:

  • Utilizing T2-weighted and diffusion-weighted (DW) MRI sequences.
  • Analyzing signal changes related to water content, cell density, and microstructural organization.

Related Experiment Videos

  • Comparing in vivo MRI with histological and in vitro MRI data.

    • Main Results:

    • Signal changes on MRI reflect histological shifts like decreasing water content and increasing cell density.
    • Diffusion-weighted imaging (DW) demonstrates microanatomical arrangement and axonal changes.
    • Specific maturational patterns are observed in the cerebral cortex, white matter, temporal lobe, and cerebellum.

    Conclusions:

    • In vivo MRI, particularly T2-weighted and DW sequences, effectively visualizes fetal brain maturation.
    • Interpreting MRI requires understanding the underlying histological changes and developmental timeline.
    • MRI provides insights into the development of both permanent and transient fetal brain structures.