Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Venomous mammals.

M J Dufton1

  • 1Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, Scotland.

Pharmacology & Therapeutics
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Mammals, like the American short-tailed shrew, possess venom, a fact scientifically established 50 years ago but largely overlooked. Research into mammalian venom toxins remains critically underexplored.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of a novel method for the identification of coevolving protein residues.

Protein engineering·2001
Same author

Do proteins learn to evolve? The Hopfield network as a basis for the understanding of protein evolution.

Journal of theoretical biology·2000
Same author

Evolutionary trace analysis of the Kunitz/BPTI family of proteins: functional divergence may have been based on conformational adjustment.

Journal of molecular biology·1999
Same author

Genetic code synonym quotas and amino acid complexity: cutting the cost of proteins?

Journal of theoretical biology·1997
Same author

The action of Taiwan cobra venom on methionine enkephalin: a useful assay for oligopeptidase content.

Toxicon : official journal of the International Society on Toxinology·1997
Same author

Foci of amino acid residue conservation in the 3D structures of the Kunitz BPTI proteinase inhibitors: how do variants from snake venom differ?

Protein engineering·1997

Area of Science:

  • Zoology
  • Toxicology
  • Mammalogy

Background:

  • Mammalian venom is not widely recognized, unlike that of reptiles.
  • Scientific evidence for venomous mammals, including shrews and solenodons, dates back to the 1940s-1950s.
  • Research in mammalian venom has significantly declined over the past two decades.

Purpose of the Study:

  • To revisit and highlight pioneering research on mammalian venom from the mid-20th century.
  • To emphasize the importance of understanding mammalian venom's implications, chemistry, and pharmacology.
  • To address the current neglect in the study of mammal venom toxins.

Main Methods:

  • Review of historical scientific literature from the 1940s and 1950s.
  • Analysis of evidence from species like the American short-tailed shrew, European shrews, and the Haitian solenodon.

Related Experiment Videos

  • Comparative discussion of venom research in mammals versus other animal groups.

    • Main Results:

    • Mammalian venom is a scientifically validated phenomenon, demonstrated over 50 years ago.
    • Despite early findings, the identity and mechanisms of action of mammalian venom toxins remain largely unknown.
    • A significant gap exists in current research compared to historical investigations.

    Conclusions:

    • The study of mammalian venom is crucial and warrants renewed scientific attention.
    • Understanding mammalian venom has significant implications comparable to other venomous animals.
    • Further research is needed to elucidate the composition and function of mammal venom toxins.