Ropivacaine compared to bupivacaine for post-tonsillectomy pain relief in children: a randomized controlled study

Ertap Akoglu1, B Cagla Ozbakis Akkurt, Kerem Inanoglu

  • 1Department of Otolaryngology, Mustafa Kemal University Medical Faculty, Araştirma Hastanesi, 31100 Antakya, Turkey.

Insights

Ropivacaine and bupivacaine provide equivalent pain relief after tonsillectomy in children. Both local anesthetics significantly reduced post-tonsillectomy pain compared to saline control.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Pain Management

Background:

  • Post-tonsillectomy pain is a significant concern in pediatric surgical care.
  • Effective pain management strategies are crucial for improving patient recovery and satisfaction.

Purpose of the Study:

  • To compare the efficacy of ropivacaine and bupivacaine for managing post-tonsillectomy pain in children.
  • To evaluate the safety and effectiveness of local anesthetic infiltration in pediatric tonsillectomy.

Main Methods:

  • A randomized controlled trial involving 46 children aged 2-12 years undergoing tonsillectomy.
  • Children were divided into three groups: bupivacaine infiltration, ropivacaine infiltration, and saline control.
  • Pain was assessed using the modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) at multiple postoperative time points.

Main Results:

  • No significant demographic differences were observed between the groups.
  • Pain scores were similar in the ropivacaine and bupivacaine groups (p>0.05).
  • Both ropivacaine and bupivacaine groups showed significantly lower pain scores compared to the control group at 1, 4, 12, 16, and 24 hours postoperatively (p<0.05).
  • Analgesic requirements and time to first analgesia were significantly improved in the anesthetic groups versus control (p<0.05).

Conclusions:

  • Local infiltration with ropivacaine is a safe and effective method for managing post-tonsillectomy pain in children.
  • Ropivacaine demonstrates equivalent efficacy to bupivacaine in reducing pediatric post-tonsillectomy pain.
  • These findings support the use of local anesthetics as a valuable component of multimodal pain management after tonsillectomy.
Abstract

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