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Published on: October 12, 2017

Serum lipids and lipoproteins in patients with documented coronary artery disease

Salahuddin1, Mohammad Aslam Siddiqui, S I Ahmad

  • 1Department of Biochemistry, Hamdard College of Medicine and Dentistry, Hamdard University, Karachi.

Pakistan Journal of Pharmaceutical Sciences
|January 18, 2006
PubMed

Insights

Lipoprotein levels offer insights into coronary artery disease (CAD) risk beyond traditional factors. This study compared lipid and lipoprotein profiles in CAD patients versus healthy individuals to assess risk factors.

Area of Science:

  • Cardiovascular Medicine
  • Biochemistry
  • Epidemiology

Background:

  • Lipoprotein subclasses provide crucial coronary artery disease (CAD) risk information.
  • Elevated lipids, lipoproteins, and lipoprotein (a) are linked to atherosclerosis and cardiovascular diseases.

Purpose of the Study:

  • To evaluate serum lipid, lipoprotein, and lipoprotein (a) levels in patients with documented coronary artery disease.
  • To compare these levels against those in normal healthy subjects.

Main Methods:

  • A case-control study involving 150 participants (100 CAD patients, 50 healthy controls).
  • Serum lipid, lipoprotein, and lipoprotein (a) levels were estimated.
  • Participants were recruited from January to June 2001.

Main Results:

  • The study aimed to compare lipid and lipoprotein profiles between CAD patients and healthy controls.
  • Specific findings on the levels and their comparison are detailed within the full study.

Conclusions:

  • Lipoprotein subclass analysis is valuable for assessing coronary artery disease risk.
  • Understanding these levels can aid in identifying individuals at higher risk for cardiovascular events.

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