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Isolation, identification and sensitivity pattern of microorganisms isolated from the urine of pregnant women

S Karim1, K I Khan

  • 1Faculty of Pharmacy, University of the Punjab, Lahore, Pakistan.

Pakistan Journal of Pharmaceutical Sciences
|January 1, 1994
PubMed

Insights

This study identified bacteria, fungi, yeast, and protozoa in pregnant women with urinary tract infections (UTIs). Norfloxacin and Metronidazole showed high susceptibility against these common UTI pathogens.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Women's Health

Background:

  • Urinary tract infections (UTIs) are common in pregnant women.
  • Identifying causative agents is crucial for effective treatment.
  • Antibiotic resistance necessitates understanding pathogen susceptibility patterns.

Purpose of the Study:

  • To detect and identify microorganisms responsible for UTIs in pregnant women.
  • To determine the antibiotic susceptibility profiles of the isolated pathogens.

Main Methods:

  • Urine samples from pregnant women with UTIs were analyzed.
  • Microorganisms were isolated, identified (bacteria, fungi, yeast, protozoa).
  • Antibiotic susceptibility testing was performed on isolated strains.

Main Results:

  • Identified pathogens included Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger, Candida albicans, and Trichomonas vaginalis.
  • High susceptibility observed for Norfloxacin, Velosef, Minocin, Nitrofurantoin, Malidixic acid, and Metronidazole.
  • Low susceptibility noted for Penbritin and Cefaloridine.

Conclusions:

  • Common microorganisms causing UTIs in pregnant women were identified.
  • Specific antibiotics demonstrate varying efficacy against these pathogens.
  • Findings guide targeted antimicrobial therapy for UTIs in pregnancy.

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