Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Viscosity studies on Mestranol.

S Akhtar1, T Ahmad, F Hassan

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi.

Pakistan Journal of Pharmaceutical Sciences
|January 18, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SAMA's principled positioning in upholding global medical ethics.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
Same author

Effect of Pr<sub>2</sub>O<sub>3</sub> addition on the mechanical properties of the mullite/ZTA composites.

Scientific reports·2026
Same author

Securing our HIV response: The PEPFAR crisis in South Africa.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025
Same author

Airway events in pregnant patients with morbid obesity undergoing caesarean delivery under general anaesthesia: a retrospective cohort study (2015-2024).

International journal of obstetric anesthesia·2025
Same author

The effects of saturated fatty acid supplements on plasma and milk concentration of fatty acid esters of hydroxy fatty acids in dairy cows.

JDS communications·2025
Same author

Iodine or Not for Low-risk Differentiated Thyroid Cancer: How Should We Implement the Findings into UK Practice? An Expert Consensus Opinion.

Clinical oncology (Royal College of Radiologists (Great Britain))·2025
Same journal

Differential effects of sevoflurane versus propofol on calmodulin expression in breast cancer patients.

Pakistan journal of pharmaceutical sciences·2026
Same journal

Neoadjuvant nivolumab plus chemotherapy in resectable NSCLC: A pharmacological outcome study.

Pakistan journal of pharmaceutical sciences·2026
Same journal

Long-term clinical outcomes of paclitaxel-coated balloon angioplasty in chronic deep vein thrombosis: A multicenter retrospective study.

Pakistan journal of pharmaceutical sciences·2026
Same journal

The hybrid drug delivery system of TCPP-Co, β-cyclodextrin and piroxicam: Spectroscopic characterization, morphological reorganization and controlled release dynamics.

Pakistan journal of pharmaceutical sciences·2026
Same journal

Stability of serum cytokeratin 18-M30 under different storage conditions for drug-induced liver injury assessment.

Pakistan journal of pharmaceutical sciences·2026
Same journal

The effect and factor analysis of potassium sodium hydrogen citrate on the formation of double J tube wall stones after ureteral stone surgery.

Pakistan journal of pharmaceutical sciences·2026
See all related articles

Mestranol solution viscosity decreases as temperature increases from 32°C to 50°C. Higher temperatures and lower viscosity correlate with Mestranol

Area of Science:

  • * Pharmaceutical Chemistry
  • * Physical Chemistry

Background:

  • * Mestranol is a synthetic steroidal hormone with estrogenic properties.
  • * Understanding its physical properties, like viscosity, is crucial for formulation and stability.

Purpose of the Study:

  • * To investigate the effect of temperature on the viscosity of Mestranol solutions.
  • * To explore the relationship between viscosity, temperature, and Mestranol degradation rates.

Main Methods:

  • * Viscosity measurements of Mestranol solutions (1x10⁻⁴ M to 4x10⁻⁴ M) in ethanol.
  • * Experiments conducted at three different temperatures: 32°C, 40°C, and 50°C.
  • * Utilized a viscometric bath for precise temperature control.

Main Results:

Related Experiment Videos

  • * Viscosity of Mestranol solutions was found to be highest at 32°C and decreased at 40°C and 50°C.
  • * A faster disappearance rate of Mestranol was observed at higher temperatures and lower viscosities.
  • * This phenomenon is attributed to triplet state species transitions under elevated thermal conditions.

    • Conclusions:

    • * Temperature significantly impacts Mestranol solution viscosity.
    • * Increased temperature and reduced viscosity accelerate Mestranol degradation, likely due to thermal transitions.
    • * Findings are relevant for optimizing storage and handling of Mestranol formulations.