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[Warfarin treatment in a general practice].

Bjørn Bratland1

  • 1Legegruppen Grandgården, Langbryggen 19, 4841 Arendal. bjorn@bratland.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|January 18, 2006
PubMed
Summary

Warfarin treatment effectively reduces thrombosis risk but increases bleeding. This study in Norwegian general practice found warfarin management comparable to other studies, indicating its continued value despite risks.

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Area of Science:

  • Cardiology
  • Pharmacology
  • General Practice

Context:

  • Warfarin is a common anticoagulant prescribed to reduce thrombosis risk.
  • General practice settings manage a significant portion of warfarin-treated patients in Norway.
  • Previous studies highlight the balance between warfarin's benefits (thrombosis prevention) and risks (bleeding).

Purpose:

  • To analyze the outcomes of warfarin treatment in a Norwegian general practice over 16 years.
  • To assess the prevalence, patient demographics, and management of warfarin therapy.
  • To evaluate the rates of therapeutic INR control, bleeding events, and thrombosis in this patient cohort.

Summary:

  • Prevalence of warfarin use increased, with older patients and more atrial fibrillation cases.
  • 57% of International Normalized Ratio (INR) measurements were within the therapeutic range.
  • Bleeding events occurred at 16 per 100 patient-years, with serious hemorrhages (2.4 per 100 patient-years) including cerebral events, comparable to other studies.

Impact:

  • Warfarin treatment, despite bleeding risks, remains a valuable and manageable option in general practice.
  • Findings support continued use of warfarin in primary care settings.
  • The study provides real-world data on warfarin management and outcomes in a general practice population.

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