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Hepatocellular carcinoma missed on gadolinium enhanced MR imaging, discovered in liver explants: retrospective
Mirace Y Karadeniz-Bilgili1, Larissa Braga, Katherine R Birchard
1Department of Radiology, University of North Carolina, Chapel Hill, North Carolina 27599-7510, USA.
Abstract:
The main purpose of this study was to determine if hepatocellular carcinomas (HCCs) missed on prospective magnetic resonance (MR) study could be identified on retrospective MR analysis, and to determine the cause for misdiagnosis. Among 555 patients who underwent liver transplantation between 1993 and 2004, 279 were imaged with MR imaging and four of these revealed HCCs in explanted livers that were not reported on prospective MR reading. The main cause of missed lesions were suboptimal image quality due to inability of patients to suspend respiration; other causes were HCC misinterpreted as high-grade dysplastic nodule and isoenhancement of HCC on early phase images.
