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Related Experiment Videos

Artecoll: the Arizona experience and lessons learned.

Millard P Thaler1, Zeena I Ubogy

  • 1Papillon Cosmetic Dermatology Center, Mesa, Arizona, USA. papillondermol@yahoo.com

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|January 19, 2006
PubMed
Summary

Artecoll offers effective, long-lasting wrinkle correction, demonstrating high patient acceptance. While generally safe, persistent nodules occurred in a few cases, highlighting a learning curve for this permanent filler.

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ArteFill: a long-lasting injectable wrinkle filler material--summary of the U.S. Food and Drug Administration trials and a progress report on 4- to 5-year outcomes.

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Area of Science:

  • Dermatology
  • Cosmetic Surgery
  • Medical Aesthetics

Background:

  • Artecoll is a novel soft tissue augmenting agent entering the U.S. market.
  • Soft tissue fillers are increasingly utilized for cosmetic facial rejuvenation.

Purpose of the Study:

  • To compare the safety and efficacy of Artecoll versus Zyderm/Zyplast for facial wrinkle correction.
  • To document practical insights gained from using Artecoll as a dermal filler.

Main Methods:

  • A randomized study involving 38 patients comparing Artecoll with Zyderm/Zyplast injections.
  • Evaluations of wrinkle improvement by patients, treating physicians, and masked evaluators.
  • Monitoring of adverse events and patient acceptance.

Main Results:

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  • Artecoll was perceived as superior to collagen fillers in most facial areas, except for the glabella and upper lip.
  • Adverse effects were comparable to collagen, with most being minor.
  • Three patients experienced treatable persistent nodules, primarily in perioral areas.

Conclusions:

  • Artecoll demonstrates effectiveness, longevity, and safety for treating facial wrinkles and folds.
  • High patient acceptance rates were observed with Artecoll treatment.
  • A learning curve exists for injecting Artecoll due to its thicker, more permanent nature.