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Answer to hypotonia: a simple hemogram.

Güler Kanra1, Mualla Cetin, Sule Unal

  • 1Department of Pediatrics Infectious Disease Unit, Hacettepe University School of Medicine, Ankara, Turkey.

Journal of Child Neurology
|January 19, 2006
PubMed
Summary

A vegetarian mother

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Area of Science:

  • Pediatrics
  • Nutrition
  • Hematology

Background:

  • Maternal diet significantly impacts infant nutrition.
  • Vitamin B12 deficiency can cause severe neurological and hematological issues in infants.
  • Exclusive breastfeeding of infants by mothers with inadequate vitamin B12 intake poses risks.

Observation:

  • A 1-year-old boy presented with weight loss, decreased activity, and psychomotor regression.
  • Initial extensive evaluations, including EEG and MRI, were inconclusive.
  • A hemogram revealed macrocytic anemia with megaloblastic bone marrow changes.

Findings:

  • Further investigations confirmed vitamin B12 deficiency.
  • Low serum vitamin B12, methylmalonic aciduria, and homocysteinemia were identified.
  • The infant's condition was linked to exclusive breastfeeding by a vegetarian mother.

Implications:

  • Highlights the critical need for vitamin B12 monitoring in breastfed infants of vegetarian mothers.
  • Underscores the potential for severe developmental consequences of vitamin B12 deficiency in infancy.
  • Emphasizes the importance of maternal nutritional status assessment for infant health outcomes.

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