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Updated: Aug 13, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
Cardiovascular complications of human immunodeficiency virus infection
Carlos S Restrepo1, Lisa Diethelm, Julio A Lemos
1Department of Radiology, Louisiana State University Health Sciences Center, 1542 Tulane Ave, Room 212, New Orleans, LA 70112, USA. crestr@lsuhsc.edu
Insights
Cardiovascular complications are common in acquired immune deficiency syndrome (AIDS). Radiologists must recognize these diverse cardiac issues, including cardiomyopathy and pulmonary hypertension, for effective patient management.
Area of Science:
- Cardiology
- Infectious Diseases
- Radiology
Background:
- Patients with acquired immune deficiency syndrome (AIDS) face various health challenges.
- While not the most common sites, the heart and great vessels can be significantly impacted by opportunistic infections and neoplastic processes in AIDS.
- Cardiovascular complications are a notable concern in AIDS patients, sometimes leading to immediate mortality.
Purpose of the Study:
- To outline the spectrum of cardiovascular complications associated with AIDS.
- To emphasize the importance of recognizing these complications through imaging.
- To assist radiologists in accurate diagnosis and treatment planning for cardiovascular manifestations in AIDS.
Main Methods:
- Review of imaging findings related to cardiovascular complications in patients with AIDS.
- Compilation of a comprehensive list of potential cardiac and vascular issues.
- Focus on the diagnostic role of medical imaging in identifying these conditions.
Main Results:
- The spectrum of cardiovascular complications in AIDS includes dilated cardiomyopathy, pericardial effusion, and pulmonary hypertension.
- Other potential findings include endocarditis, thrombosis, embolism, vasculitis, coronary artery disease, aneurysms, and cardiac tumors.
- These complications, while not always the primary presentation, are significant and require radiologic recognition.
Conclusions:
- Cardiovascular complications are a significant aspect of acquired immune deficiency syndrome (AIDS).
- Radiologists play a crucial role in identifying these diverse cardiac and vascular manifestations through imaging.
- Familiarity with the imaging appearance of these conditions is essential for accurate diagnosis and treatment planning in AIDS patients.
Abstract:
The heart and great vessels are not the sites most frequently affected by opportunistic infections and neoplastic processes in patients with acquired immune deficiency syndrome (AIDS). However, cardiovascular complications occur in a significant number of such patients and are the immediate cause of death in some. The spectrum of cardiovascular complications of AIDS that may be depicted at imaging includes dilated cardiomyopathy, pericardial effusion, human immunodeficiency virus-associated pulmonary hypertension, endocarditis, thrombosis, embolism, vasculitis, coronary artery disease, aneurysm, and cardiac involvement in AIDS-related tumors. To aid accurate diagnosis and appropriate treatment planning, radiologists should be familiar with the imaging appearance of each of these complications.
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