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Updated: Aug 13, 2026
Manipulating the Murine Lacrimal Gland
Published on: November 18, 2014
Recurrent acute lymphoblastic leukemia presenting in the lacrimal gland
Scott Cardone1, Michael T Yen, Patricia Chévez-Barrios
1Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX 77030, USA.
Abstract:
A 14-year-old girl with a history of acute lymphoblastic leukemia presented with periorbital swelling of the right eyelid associated with enlargement of the lacrimal gland and cervical lymphadenopathy. Radiographic imaging showed diffuse enlargement and enhancement of the right lacrimal gland. The patient underwent an incisional biopsy of the lacrimal gland that showed atypical lymphocytes consistent with recurrent acute lymphoblastic leukemia. The lacrimal gland is a rare extramedullary site for recurrence of this disease.