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Updated: Aug 13, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
[Massive transaminase rise after vicryl mesh wrapping for liver trauma]
C Nguyen Manh1, C Milsmann, H Becker
1Klinik für Allgemeinchirurgie, Universitätsklinikum Göttingen.
Abstract:
Mesh wrapping hepatorrhaphy is an established method to control severe hepatic bleeding after trauma. Besides the multiple advantages of this technique, only a few complications are described in literature. We report a patient with severe liver trauma showing ischemia of the liver caused by post-traumatic edema and compression of the liver after mesh wrapping hepatorraphy to control the bleeding. To avoid this complication, early and frequent control of liver enzymes is highly recommended and, in case of elevation, laparotomy and decompression should be performed.