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[Concomitant depression and its treatment].

C Kaufmann1, P Panayiotou, M Dossenbach

  • 1Ludwig Boltzmann-Institut für Neuro-Rehabilitation und -Prophylaxe, Rankweil.

Wiener Medizinische Wochenschrift (1946)
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Fluoxetine (Fluctine) is an effective antidepressant for elderly patients with depression, offering a fast onset and minimal side effects. It is particularly beneficial for those with accompanying physical illnesses, though patients with organic-brain conditions may respond less favorably.

Area of Science:

  • Geriatric Medicine
  • Psychiatry
  • Pharmacology

Context:

  • Depression frequently co-occurs with chronic physical illness and disability in the elderly.
  • Treatment requires a comprehensive approach addressing both physical and psychological symptoms.
  • Pharmacotherapy, psychotherapy, and physiotherapy are key components of management.

Purpose:

  • To evaluate the efficacy and tolerability of Fluoxetine (Fluctine) in elderly patients with depression.
  • To compare Fluoxetine's effectiveness against other antidepressants in this population.
  • To identify patient subgroups that may respond differently to antidepressant treatment.

Summary:

  • Fluoxetine demonstrated effectiveness in a randomized patient group, characterized by rapid onset, minimal side effects, and a slight increase in drive.

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  • A significant portion of patients (one-third) did not respond to Fluoxetine or alternative antidepressants.
  • Patients with organic-brain illness showed poorer response rates, consistent with existing literature.

    • Impact:

    • Fluoxetine can be a recommended option for managing depression in elderly patients, especially those with co-existing physical conditions.
    • Highlights the importance of considering underlying organic conditions when prescribing antidepressants.
    • Emphasizes the need for individualized treatment strategies in geriatric depression management.