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[Induction of sarcoma by resorbable osteosynthesis material in the rat. A preliminary report]
T Hoppert1, H Pistner, M Stolte
1II. Chirurgische Klinik des Klinikums Bayreuth, Universität Würzburg.
Zeitschrift Fur Orthopadie Und Ihre Grenzgebiete
|May 1, 1992
Abstract:
In an experiment testing the resorption of Poly-l-lactate in the back muscles of Cara rats a foreign body sarcoma occurred in two rats. 20 months after implantation of a body of high molecular weight poly-l-lactate a malignant fibrous histiocytoma developed in one rat. A soft tissue tumor, which was classified according to the immune-histiochemical analysis as a neurogenic sarcoma, developed 23 months after the implantation of a body of injection-casted poly-l-lactate of high molecular weight in a second rat.