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Updated: Feb 10, 2026
08:36
Quantifying Yersinia pseudotuberculosis Type III Secretion System Activity Following Iron Starvation and Anaerobic Growth
Published on: May 31, 2024
936
A spontaneous Yersinia pseudotuberculosis-infection in a monkey-colony
Summary
Spontaneous Yersinia pseudotuberculosis infection affected African Green Monkeys and Squirrel Monkeys. The digestive system was most impacted acutely, with severe chronic changes in lymphatic tissues, spleen, and liver.
Area of Science:
- Veterinary Pathology
- Primate Infectious Diseases
- Microbial Pathogenesis
Background:
- Yersinia pseudotuberculosis (Y.p.) is a bacterial pathogen with a broad host range.
- Spontaneous infections in non-human primates are valuable models for understanding disease dynamics.
Observation:
- This report details a spontaneous Yersinia pseudotuberculosis infection in one African Green Monkey and nine Squirrel Monkeys.
- Clinical, laboratory, and pathological findings were systematically documented.
Findings:
- The digestive system showed the most significant alterations during the acute phase of Y.p. infection.
- Subacute and chronic phases were characterized by severe pathological changes in lymphatic tissues, spleen, and liver.
Implications:
- Understanding Y.p. pathogenesis in primates is crucial for managing captive and wild populations.
- This case study contributes to the knowledge of Yersinia infections in non-human primates, informing diagnostic and therapeutic strategies.
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