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[Stewart-Treves syndrome].

Miguel Echenique-Elizondo1, Ana Tuneu-Valls, José Zubizarreta

  • 1Unidad Docente de Medicina, Facultad de Medicina, Universidad del País Vasco, San Sebastián, Guipúzcoa, Spain. gepecelm@sc.ehu.es

Cirugia Espanola
|January 20, 2006
PubMed
Summary
This summary is machine-generated.

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Lymphangiosarcoma, a rare vascular tumor often linked to chronic lymphedema, presents a poor prognosis, particularly in Stewart-Treves syndrome cases. This study analyzed five patients, highlighting challenges in treatment and outcomes.

Area of Science:

  • Vascular Oncology
  • Lymphedema Research
  • Surgical Pathology

Context:

  • Lymphangiosarcoma is an uncommon malignancy arising in chronic lymphedema.
  • Stewart-Treves syndrome is a specific presentation of lymphangiosarcoma post-mastectomy and radiotherapy.
  • Congenital lymphedema can also predispose to secondary malignancies.

Purpose:

  • To analyze the clinical characteristics, treatment, and outcomes of lymphangiosarcoma.
  • To evaluate the prognosis of lymphangiosarcoma in patients with longstanding lymphedema.
  • To report on cases of Stewart-Treves syndrome and secondary lymphangiosarcoma.

Summary:

  • Five cases of lymphangiosarcoma were reviewed: three with Stewart-Treves syndrome and two with congenital lymphedema.
  • Patient demographics included four females and one male.

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  • Treatments involved radical surgery (amputation, disarticulation) and chemotherapy/radiotherapy; outcomes were generally poor with high early mortality.

    • Impact:

    • This case series underscores the aggressive nature and poor prognosis of lymphangiosarcoma, especially in the context of Stewart-Treves syndrome.
    • Findings emphasize the need for vigilant monitoring in patients with chronic lymphedema.
    • The study contributes to understanding the clinical behavior of this rare vascular tumor.