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Related Experiment Video

Updated: Jul 11, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Predictors of long-term weight maintenance.

Neeltje Vogels¹, Kristel Diepvens, Margriet S Westerterp-Plantenga

¹Department of Human Biology, Maastricht University, The Netherlands. N.Vogels@HB.Unimaas.NL

Obesity Research

|January 20, 2006

Summary

Successful weight maintenance after weight loss depends on increased dietary restraint and a high baseline resting metabolic rate. Factors like body composition and low dieting frequency also predict long-term weight control.

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Area of Science:

Obesity research
Metabolic studies
Behavioral science

Background:

Weight regain is a common challenge after successful weight loss.
Understanding predictors of weight maintenance is crucial for effective obesity management.
Long-term studies are needed to identify factors influencing weight regain.

Purpose of the Study:

To investigate factors predisposing to weight regain in a long-term weight maintenance study.
To evaluate variables associated with successful weight maintenance after a period of weight loss.

Main Methods:

Longitudinal study of healthy men and women (n=91) aged 18-65 with a baseline BMI of 30.2 ± 3.1 kg/m².
Measurements taken before and after a very-low-energy diet, with follow-up of at least 2 years.
Analysis of weight change, body composition, resting metabolic rate, dietary restraint, and dieting frequency.

Main Results:

Mean weight loss was 7.9 kg, with 113.8% weight regain.
Increased dietary restraint was negatively associated with BMI regain (r = -0.47, p < 0.05).
Higher baseline resting metabolic rate (r = -0.38, p = 0.01) and fat mass (r = -0.24, p = 0.05) predicted better weight maintenance.

Conclusions:

Weight maintenance is multifactorial, involving energy expenditure, body composition, and eating behavior.
Key predictors include increased dietary restraint, high baseline resting metabolic rate, and favorable body composition.
A stable body weight and low frequency of dieting contribute to successful long-term weight management.