Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pathophysiology of erectile dysfunction.

Iñigo Sáenz de Tejada1, Javier Angulo, Selim Cellek

  • 1Fundación para la Investigación y el Desarrollo en Andrología, Madrid, Spain.

The Journal of Sexual Medicine
|January 21, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of a non-invasive oestrous synchronisation protocol on sexual behaviour in Sprague-Dawley rats.

The journal of sexual medicine·2026
Same author

Combination therapy for acute Peyronie' s disease: a success story of translation from bench to bedside.

Nature reviews. Urology·2026
Same author

Senicapoc in Patients with Idiopathic Pulmonary Fibrosis or Other Progressive Fibrotic Interstitial Lung Diseases: Protocol for a Randomised, Double-Blind, Placebo-Controlled, Multicentre Phase II Trial.

Diagnostics (Basel, Switzerland)·2026
Same author

Gender Differences in Circulating TFAM Levels Are Associated with Functional Impairment and Sarcopenia.

Biomedicines·2026
Same author

Support, Monitoring, and Reminder Technology for Mild Dementia (SMART4MD) for People With Mild Cognitive Impairment and Their Informal Caregivers: Cost-Effectiveness Analysis.

JMIR human factors·2026
Same author

Evaluation of a combination of off-label PDE5 inhibitor and tamoxifen in acute Peyronie's disease.

The journal of sexual medicine·2026

Erectile dysfunction (ED) arises from disruptions in psychological, neurological, hormonal, vascular, or cavernosal systems. Understanding these complex physiological mechanisms is key to developing effective prevention and treatment strategies for ED.

Area of Science:

  • Urology
  • Sexual Medicine
  • Physiology

Background:

  • Normal erectile function involves multiple regulatory systems.
  • Disruptions in psychological, neurological, hormonal, vascular, and cavernosal factors can cause erectile dysfunction (ED).

Framework:

  • An international consultation involved over 200 multidisciplinary experts from 60 countries.
  • Seventeen committees, including one focused on ED pathophysiology with seven experts from five countries, contributed over a 2-year period.

Implementation:

  • Expert opinion was formed through grading evidence-based literature, committee discussions, and public debate.
  • The review focused on neurogenic, vascular, and cavernosal factors in ED.

Implications:

Related Experiment Videos

  • Key findings include the epidemiology and classification of neurogenic ED.
  • Vascular ED is associated with atherosclerosis, hypertension, and diabetes, involving mechanisms like arterial remodeling and impaired vasodilation.
  • Understanding disease interference with penile erection physiology aids ED prevention and treatment strategies.